Rapid onset of protection against infectious bovine rhinotracheitis with a modified-live virus multivalent vaccine.

A DNA Vaccine Formulated with Chemical Adjuvant Provides Partial Protection against Bovine Herpes Virus Infection in Cattle

Bovine herpesvirus-1 (BoHV-1) is the causative agent of bovine infectious rhinotracheitis, an important disease worldwide. Although conventional BoHV-1 vaccines, including those based on the use of modified live virus and also inactivated vaccines, are currently used in many countries, they have several disadvantages. DNA vaccines have emerged as an attractive approach since they have the poten...

Response to modified live and killed multivalent viral vaccine in regularly vaccinated, fresh dairy cows.

Vaccination programs for viral pathogens in the dairy industry span the full spectrum of possibilities even though few of these have been evaluated in field situations. One such program is the vaccination of fresh cows 30 to 60 days postpartum with modified live viral (MLV) vaccines. The purpose of this study was to evaluate the antibody response to booster vaccinations during this period. The ...

Use of Sodium Alginate Adjuvant in Preparation of a Formalin Killed Vaccine Against Infectious Bovine Rhinotracheitis

Detection of antibody against infectious bovine rhinotracheitis glycoprotein gE in aborted cattle in Mashhad, Iran

Infectious Bovine Rhinotracheitis is a highly contagious disease caused by the bovine herpes virus-1 (BoHV-1), resulting in significant losses to livestock around the world. BoHV-1 is a major pathogen of cattle, primarily associated with respiratory/genital tract infections and abortion. In the present study, we determined the presence of antibodies in 120 serum samples of cattle with the histo...

Sensitivity of infectious bovine rhinotracheitis virus to ether.

The sensitivity of 12 field isolates of infectious boviine rhinotracheitis (IBR) virus and four commercial modified-live infectious bovine rhinotracheitis virus vaccine strains was determined after exposure to 20% ethyl ether (anesthetic) for 16 h at 4 c. The infectivity of five field strains was reduced by varying degrees, whereas seven were found to be resistant. Three vaccine strains were mo...